My answer to Can using an Estrogen Blocker with a DHT Inhibitor (Finasteride) be healthy? Fruitful? Or devastating?
Answer by Nature Crazy:
Propecia also referred to as Finasteride is a common main stream hair loss treatment recommended by dermatologists and doctors for thinning hair. It prevents the formation of DHT by decreasing impeding 5-alpha-reductase enzyme. As a result, testosterone levels increase but so does excess estrogen which is not good for the body. This is correct.
Excess Estrogen negatively impacts glucose metabolism, so the greater the amount of estrogen in a male, the more damaging effects on insulin sensitivity. This also explains why finasteride loses its punch as our Sex Hormone Binding Gobulin levels increase. Also because it impedes 5-alpha reductase in an unnatural way it affects the Gaba receptors in the brain which again can lead to side effects such as anxiety, depression, and brain fog.
Regardless, there are safer natural ways for maintaining existing hair and reversing hair loss. Many people (The manufacturers of Propecia) have pointed to an overproduction of the enzyme DHT as the culprit for hair loss but the truth is it’s more complex than that. Everyone harbors this particular enzyme in their scalp and hair follicle, yet not everyone loses their hair now do they? No doubt that DHT does play a role in Hair Loss, but hair loss is not singularly rooted in DHT. In fact, you should really be thinking of it as more of a message-bearer. What we should also be focusing on is shielding, preventing, and reducing the enzymes and proteins that are precipitated by DHT.
There are a variety of inflammatory incidents that happen before and after DHT as well as different bodily occurrences that have an impact on our production of DHT in the scalp. A perfect example of this is the fact that DHT stimulates TGF-Beta. This creates a domino effect wherein collagen enzymes are stimulated, which then initiates the follicle degeneration process. Certain cytokines, such as Tumor Necrosis Factor alpha, Superoxide, Reactive Oxygen Species, Prostaglandin imbalances, stress hormone elevation, and prolactin production can all leave their mark as well.
Managing all these factors as opposed to just managing DHT are critical to staving off hair loss. So what triggers these inflammatory events that cause your hormones to get out of whack in the first place?
Weight gain, Excessive physical or mental stress, Environmental Pollution, Poor diet and eating disorders, lack of vitamins and minerals, and a build up of toxins in the body.
Do genetics play a role? Yes, but the field of epigenetics (which was a direct result of the work carried out at the human genome project) has shown that while the DNA in our make-up remains fixed the epigenome continually responds to our diet and living conditions, enabling an entire alteration in genetic expression. In other words, your genes just determine a supsceptivity towards thinning and hair loss. There are many ways for halting the process naturally for ALL types of hair loss.
If you want more information on this I suggest going to our website at www.NatureCrazy.com or watching our video on the matter.